Organic Chemistry 215H
نویسنده
چکیده
In the 1950’s Francis Crick formulated the “central dogma of molecular biology” in which information flows from DNA to RNA and finally to protein. Although certain exceptions to this model have emerged over the past 50 years, such as the discovery of RNA as the source of genetic information in certain viruses and the role of catalytic RNA in translation, this formulation has proved to be nearly ubiquitous. With this in mind it’s only appropriate to think of protein as the functional macromolecule of life; with DNA providing information storage and RNA acting as both decoder and messenger. However, as a consequence of this reality, proteins must be capable of performing an incredible number of both highly varied and highly specific tasks. For example, one protein must be capable of importing glucose across an impermeable cellular membrane while another protein must be capable of recognizing and catalyzing the phosphorylation of target macromolecules upon stimulation. Therefore, nature cleverly designed a single class of biomacromolecules capable of performing disparate functions. Among the varied responsibilities of proteins are molecular and ion transport, signaling, structural integrity, and reaction catalysis. Remarkably, nature has used many of the principles now common to you, as students of organic chemistry, to accomplish the extraordinary demands made of proteins.
منابع مشابه
Microwave-assisted preparation of Nـ alkyl 2ـ ketomethyl quinolines on Solvent-free Conditions
متن کامل
Microwave-accelerated preparation of Nـ alkyl 2ـ ketomethyl quinoline Derivatives
A series of Nـ alkyl 2ـ ketomethylquinoline derivatives were synthesis by reaction of benzoyl chloride derivatives with Nـ methyl quinaldine iodide in the presence of triethyl amine under microwave irradiation. Enaminone form of the product study by spectroscopy method. The result revealed the Nـ alkyl 2ـ ketomethylquinoline the fixed enaminone tautomer.
متن کاملMicrowave-assisted Synthesis of Nـ alkyl 2ـ ketomethyl quinoline Derivatives Under Solvent-free Conditions
A series of Nـ alkyl 2ـ ketomethylquinoline derivatives were synthesis by reaction of benzoyl chloride derivatives with Nـ methyl quinaldine iodide in the presence of triethyl amine under microwave irradiation. Enaminone form of the product study by spectroscopy method. The result revealed the Nـ alkyl 2ـ ketomethylquinoline the fixed enaminone tautomer.
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تاریخ انتشار 2003